Shares of Biocon Ltd fell as much as 7.6 per cent to Rs 346.70 in early trade, its biggest intra-day percentage loss since March 2.

US FDA issued 10 observations pointing at aseptic practices after an inspection at the drugmaker's plant in Bengaluru, media reports said citing a Form 483 issued on the regulator's website

The regulator earlier issued a form 483 with 8 observations in April for the Bengaluru facility

Shares of other Indian drugmakers were also down - Sun Pharmaceutical Industries Ltd was down as much as 4.5 per cent, Cadila Healthcare Ltd lost as much as 2.9 per cent.

Nifty pharma index slipped as much as 2.5 per cent in its biggest intraday pct loss since May 29

Up to Thursday's close, Biocon's stock had risen 18.4 per cent this year.